At present, there is little basic biomedical research on calcium and bone metabolism in Thailand. One of the reasons for this lack of interest in this field is that metabolic bone diseases are mostly chronic, not easily diagnosed in the early stages, and are not life threatening compared to other diseases such as cardiovascular or infectious diseases. However, incidence of bone diseases has been known to increase dramatically in recent years with prolonged life expectancy and the increase in the elderly population in both developed countries and developed countries including Thailand. Undoubtedly, bone diseases will have a negative socioeconomic impact in Thailand in the very near future. It is thus necessary for Thailand to encouraged basic research in the field of calcium and bone metabolism which will ultimately lead to better understanding of the etiology and mechanisms of bone diseases, effective treatment and prevention. Multidisciplinary research approach is the best way to tackle complex research problems because it provides alternative views as well as ways to solve the problem.
Our research group known as the Consortium for Calcium and Bone Research or COCAB was established in 2003 as interdisciplinary research unit in the Center of Excellence of the Faculty of Science, Mahidol University. The present members include academicians from the Faculty of Science and Faculty of Medicine, Ramathibodi Hospital, Mahidol University, as well as from other universities.
We carry out research in two major projects; Prolactin, its role in the regulation of calcium and bone metabolism and The regulation of bone remodeling in health and disease.
- To serve as an interdisciplinary research center for joint bioscience and clinical science research in calcium and bone metabolism
- To produce high Quality publications as well as knowledge that can be applied to help solve health problems in Thai population.
- To produce graduate students and scientists with multidisciplinary research experience and teamwork spirit
- Prolactin : its role as a calcium regulating hormone
- Prolactin and electrolyte transport the endometrium
- Signal transduction pathways of prolactin
- Cellular and molecular mechanism of the intestinal calcium transport
- Disorders of calcium and bone metabolism in metabolic bone diseases
- How nonimpact exercise affect calcium absorption and bone remodeling
- How brain controls bone